Occlusal morphology pdf

All marker expressions were significantly decreased. Cyclopamine-antagonizing Smo inhibits Shh signaling activity Taipale et al. Occlusal force regulates the expression of BBS7 to mediate Shh signaling activity, which orchestrates cell migration for proper PDL homeostasis. However, the present study could not elucidate how each BBS family gene is closely associated with occlusal force. The current human study provides fundamental importance to explain how vigorous PDL homeostasis is maintained by occlusal force.

Maintenance of BBS7 expression with Shh signaling activity in primary cilia is of fundamental importance by occlusal force. Occlusal hypofunction is closely associated with these relationships. Furthermore, to sustain PDL homeostasis, proper occlusal force is indispensable. PEC and SL contributed to analysis, drafted the manuscript, and critically revised the manuscript.

H-YK contributed to analysis and drafted the manuscript. D-JL contributed to analysis and critically revised the manuscript. All authors gave their final approval and agree to be accountable for all aspects of the work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors, and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Aung, P. Blacque, O. Loss of C. Genes Develop. Donnelly, E. Guo, D. Physiology-Cell Physiol.

Hampl, M. Role of Primary Cilia in Odontogenesis. Dent Res. Hayashi, A. Angle Orthod. Hisamoto, M. Irigoin, F. Badano, J. Cg 12 4 , — Ishida, Y. Itohiya, K. Dent Oral Craniofac. Jeon, H. Jcm 10 8 , Jin, H. Cell 7 , — Kaneko, S. Periodontal Res. Kasahara, Y. Kim, J. Kim, K. Lamalice, L. Endothelial Cell Migration during Angiogenesis.

Lee, D. Bio-implant as a Novel Restoration for Tooth Loss. Lei, X. Cell Death Dis 11 4 , Lim, C. Love, M. Genome Biol. Men, Y. Cel 54 5 , — Miyagawa, A. Motokawa, M. Oral Invest. Nachury, M. Cell 6 , — Ono, Y. Oral Rehabil. Ouchani, F. New Drugs 33 1 , 75— Panny, A. Robbins, D. Signal Transduction , 1— Seo, B. The Lancet , — Seo, S. Plos Genet. Shimizu, Y. Oral Biol. Shimomoto, Y. Sims, M. The two noteworthy changes regarding the socket subsequent to both hyper- and hypofunction are its in- creased area and changed location within the mandib- ular borders.

The increase in socket area, especially under hypofunction, reflected the sum total of the den- tal and periodontal changes. This observation contra- dicts reports stating that atrophy of the PDL is the usual response to hypofunction Grant e t al. On the other hand, results agreeing with those found in the present study were reported by Bondevik , albeit after only a short days experimental period Fig. The attrition pattern caused by altered grinding movements of hypofunction.

He considers augmented periodontal induced by shortening of the left lower incisor. Steigman et al. That such crease was found to originate in the cementum-related changes do occur was shown by Steigman et al. This differential re- change in dentin production under condition of pro- sponse of these two PDL segments to altered functional longed hypofunction.

Hypofunction A : increased socket area, mainly seen in the enamel-related region. Hyperfunc- tion B : socket area somewhat increased see Table 1 ; C: control group.

Thus, in the current study, the effect of an icantly increased total anterior vertical dimension increment in PDL and of enlarged tooth volume is ex- under hyperfunction Table 2 reflect the differential pressed in increased socket area.

This anatomical response again Beertsen, W. Everts, and K. Hoeben Loss of connective tissue supports the functional matrix theory of Moss When addressing the issue of socket location in the Berkovitz, B. The force exerted A feasible assumption would be that Coolidge, D.

Grant, D. Stern, and F. Everett Periodontics. Mosby Co. Louis, MO, 5th ed. The positional change in the vertical dimension of Kiliaridis, S. Engstrom, and B. Thilander The relationship the socket was not accompanied by a significant change between masticatory function and craniofacial morphology. A in the horizontal direction Table 1.

Considering the cephalometric longitudinal analysis in the growing rat fed a soft equal increase in the posterior mandibular length in diet. Kiliaridis, and C. Engstrom Effect of low mas- ticatory function on condylar growth. Presented to the European reasonable that dental and skeletal responses to Orthodontic Society Abstract No.

Jensen, E. Moller, and A. Bjork Craniofacial ion. Previous studies in rats have shown that altered Orthod. Kronfeld, R. McFadden, L. McFadden, and D. Precious Effect of The significant changes observed in the posterior controlled dietary consistency and cage environment on the rat mandibular growth.

Weinreb Role of attrition and occlusal pofunction probably reflect the altered muscle activity contact in the physiology of the rat incisor. Prevention of at- in the posterior mandibular region. These findings trition and occlusal contact in the non-articulating incisors.

Leipzig, W. Engelman, cited by Gra- than by the anterior area. In: Orthodontics, Current The lack of further significant differences between Principles and Techniques. Mechanics of mandibular movement 5.

Criteria for optimum functional occlusion 6. Etiology of functional disturbances in the masticatory system 8. Signs and… Expand. Save to Library Save. Create Alert Alert. Share This Paper. Background Citations.

Methods Citations. Results Citations. Topics from this paper. Citation Type. Has PDF.